首页 蛋白库 基因库 产品 会员服务
位置：首页 > 产品库 > Synephrine HCl
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Synephrine HCl
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Synephrine HCl图片
CAS NO:5985-28-4

Synephrine (Oxedrine) hydrochloride 是一种生物碱，是一种 α-adrenergic 和 β-adrenergic 激动剂，来自枳壳。
Cas No.5985-28-4
别名辛弗林盐酸盐; Oxedrine hydrochloride
化学名4-[1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride
Canonical SMILESCNCC(C1=CC=C(C=C1)O)O.Cl
分子式C9H13NO2.HCl
分子量203.67
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Synephrine hydrochloride (Oxedrine hydrochloride) is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium, it has sympathomimetic and structural similarities to ephedra and ephedrine alkaloids[1][2].

Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine[2].

References:
[1]. Thomas JE, et al. STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J. 2009;36(6):586-90.
[2]. Huang YT, et al. Hemodynamic effects of synephrine treatment in portal hypertensive rats. Jpn J Pharmacol. 2001 Feb;85(2):183-8.

 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024