NLRP3-IN-11

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NLRP3-IN-11

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2769040-91-5

NLRP3-IN-11 是一种NLRP3蛋白抑制剂。NLRP3-IN-11 具有生物活性，IC₅₀值<0.3 μM。NLRP3-IN-11 可用于炎症和退行性疾病的研究，包括 NASH、动脉粥样硬化和其他心血管疾病、阿尔茨海默病、帕金森病、糖尿病、痛风和许多其他自身炎症性疾病。

生物活性

NLRP3-IN-11 is aNLR family pyrin domain containing 3 (NLRP3) proteinsinhibitor. NLRP3-IN-11 has biological activity forNLRP3with anIC₅₀value of ＜0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases^[1].

IC₅₀& Target

NLRP3

<0.3 μM (IC₅₀)

体外研究
(In Vitro)

NLRP3-IN-11 has biological activity with an IC₅₀value of ＜0.3 μM in human PBMC NLRP3 assay^[1]

分子量

344.80

Formula

C₁₇H₁₇ClN₄O₂

CAS 号

2769040-91-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.