CAS NO: | 105879-42-3 |
生物活性 | Cephalexin (Cefalexin) hydrochloride monohydrate is a potent, orally active new semisynthetic cephalosporinantibioticwith a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride monohydrate targets penicillin-binding proteins (PBPs) to inhibitbacterialcell wall assembly. Cephalexin (Cefalexin) hydrochloride monohydrate is used for the research of pneumonia, strep throat, andbacterialendocarditis, et al[1][2]. | ||||||||
体外研究 (In Vitro) | Cephalexin (Cefalexin) hydrochloride monohydrate (10 μg/mL) disrupts polymer peptidoglycan (PG) biogenesis by inactivating enzymes called penicillin-binding proteins (PBPs)[1].Cephalexin (Cefalexin) hydrochloride monohydrate inhibits a broad spectrum of grampositive and gram-negative organisms with MIC values of 2, 2, 2, 2, 4, 4.4 and 5.7 μg/mL forBacillus anthracis,Edwardsiella taFda,Vibrio cholera,Pasteurella multocida,Edwardsiella tarda,Alcaligenes spandProteus rettgeri, respectively[2]. | ||||||||
体内研究 (In Vivo) | Cephalexin (Cefalexin) hydrochloride monohydrate (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial[2].
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Clinical Trial | |||||||||
分子量 | 401.87 | ||||||||
Formula | C16H20ClN3O5S | ||||||||
CAS 号 | 105879-42-3 | ||||||||
中文名称 | 头孢氨苄单盐酸盐 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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