位置:首页 > 产品库 > Cephalexin hydrochloride monohydrate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Cephalexin hydrochloride monohydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cephalexin hydrochloride monohydrate图片
CAS NO:105879-42-3

头孢氨苄单盐酸盐
Cefalexin hydrochloride monohydrate
Cephacillin hydrochloride monohydrate
Cephalexin (Cefalexin) hydrochloride monohydrate 是一种口服有效的新型半合成头孢菌素抗生素 (antibiotic),具有广泛的抗菌谱。Cephalexin (Cefalexin) hydrochloride monohydrate 对多种革兰氏阳性和革兰氏阴性细菌具有抗菌活性。Cephalexin (Cefalexin) hydrochloride monohydrate 靶向青霉素结合蛋白 (PBPs),以抑制细菌细胞壁组装。Cephalexin (Cefalexin) hydrochloride monohydrate 用于肺炎、链球菌性咽喉炎、细菌性心内膜炎等的研究。
生物活性

Cephalexin (Cefalexin) hydrochloride monohydrate is a potent, orally active new semisynthetic cephalosporinantibioticwith a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride monohydrate targets penicillin-binding proteins (PBPs) to inhibitbacterialcell wall assembly. Cephalexin (Cefalexin) hydrochloride monohydrate is used for the research of pneumonia, strep throat, andbacterialendocarditis, et al[1][2].

体外研究
(In Vitro)

Cephalexin (Cefalexin) hydrochloride monohydrate (10 μg/mL) disrupts polymer peptidoglycan (PG) biogenesis by inactivating enzymes called penicillin-binding proteins (PBPs)[1].
Cephalexin (Cefalexin) hydrochloride monohydrate inhibits a broad spectrum of grampositive and gram-negative organisms with MIC values of 2, 2, 2, 2, 4, 4.4 and 5.7 μg/mL forBacillus anthracis,Edwardsiella taFda,Vibrio cholera,Pasteurella multocida,Edwardsiella tarda,Alcaligenes spandProteus rettgeri, respectively[2].

体内研究
(In Vivo)

Cephalexin (Cefalexin) hydrochloride monohydrate (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial[2].

Animal Model:Male Swiss-Webster mice with infected bacterial[2]
Dosage:0-50 mg/kg
Administration:Oral administration; for 3.5 hours
Result:Had antibacterial activity againstStreptococcus pyogenes,Streptococcus pneumoniae,Staphylococcus aureusand severalgram-negative speciesmice.
Clinical Trial
分子量

401.87

Formula

C16H20ClN3O5S

CAS 号

105879-42-3

中文名称

头孢氨苄单盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024