Clavulanate potassium

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CAS NO:

61177-45-5

克拉维酸钾

Clavulanate potassium 是一种高效的β-lactamase抑制剂，可作为抗生素。

生物活性

Clavulanate potassium is a potentβ-lactamaseinhibitor and acts as anantibiotic^[1]^[2].

IC₅₀& Target

β-lactamase^[1]

体外研究
(In Vitro)

Clavulanate potassium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase^[1].
Clavulanate potassium (0.25 mg/L, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L^[2].

Clinical Trial

分子量

237.25

性状

Solid

Formula

C₈H₈KNO₅

CAS 号

61177-45-5

中文名称

克拉维酸钾

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

H₂O : 33.33 mg/mL(140.48 mM;ultrasonic and adjust pH to 2 with HCl)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	4.2150 mL	21.0748 mL	42.1496 mL
5 mM	0.8430 mL	4.2150 mL	8.4299 mL
10 mM	0.4215 mL	2.1075 mL	4.2150 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。