Dicloxacillin Sodium

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CAS NO:

343-55-5

双氯西林钠

Dicloxacillin sodium 是青霉素类的 β 内酰胺抗生素 (β-lactam antibiotic)，可用于革兰氏阳性菌感染的研究。Dicloxacillin sodium 有效抑制 β-内酰胺酶产生的微生物如金黄色葡萄球菌。

生物活性

Dicloxacillin sodium is aβ-lactamantibioticof the penicillin family. Dicloxacillin sodium against Gram-positive bacteria. Dicloxacillin sodium is active against β-lactamase-producing organisms such asStaphylococcus aureus^[1].

体外研究
(In Vitro)

Dicloxacillin exhibits EC₅₀values of 0.06 and 0.50 mg/L in ATCC 25923 and E19977, respectively. Dicloxacillin exhibits MIC values of 0.125 and 0.5 mg/L in ATCC 25923 and E19977 with pH 7.4, respectively^[2].

体内研究
(In Vivo)

Dicloxacillin exhibits therapeutic activity in murine peritonitis-sepsis model and all the mice are survivied^[3].

Animal Model:	Female outbred Swiss Webster mice (Murine peritonitis-sepsis model)^[3].
Dosage:	125 mg/kg.
Administration:	IV injection, single doses.
Result:	All the mice survived.

Clinical Trial

分子量

492.31

Formula

C₁₉H₁₆Cl₂N₃NaO₅S

CAS 号

343-55-5

中文名称

双氯西林钠

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.