Galactofucan

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Galactofucan

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

9061-39-6

Fucogalactan

Galactofucan (Fucogalactan) 是一种硫酸多糖。Galactofucan 可以从棕色海藻Saccharina longicruris中提取，具有抗凝血、抗肿瘤、抗血栓形成、抗炎、抗病毒等特性。Galactofucan 对HSV-1和HSV-2具有抗病毒活性，IC₅₀值分别为 0.76 和 1.34 μg/mL 。Galactofucan 可用于癌症和炎症的研究。

生物活性

Galactofucan (Fucogalactan) is a sulfated polysaccharide. Galactofucan can be extracted from brown seaweedSaccharina longicruriswith anticoagulant, anti-tumor, anti-thrombosis, anti-inflammatory and antiviral properties. Galactofucan shows antiviral activities toHSV-1andHSV-2withIC₅₀s of 0.76 and 1.34 μg/mL, respectively. Galactofucan can be used for the research ofcancerand inflammation^[1]^[2].

IC₅₀& Target

HSV-1

0.76 μg/mL (IC₅₀)

HSV-2

1.34 μg/mL (IC₅₀)

体外研究
(In Vitro)

Galactofucan (0-100 μg/mL; 48 h) shows antiviral activities towards HSV-1 and HSV-2 with IC₅₀s of 0.76 and 1.34 μg/mL, respectively^[1].

体内研究
(In Vivo)

Galactofucan (10-100 mg/kg; i.p. once) (extracted fromAgaricus bisporus) shows anti-inflammatory activity^[2].

Animal Model:	Male Swiss mice with acetic acid intraperitoneal injection^[2]
Dosage:	10, 30 and 100 mg/kg
Administration:	Intraperitoneal injection; 10-100 mg/kg once
Result:	Repressed acetic acid-induced abdominal constriction, inhibited leukocytes migration and peritoneal capillary permeability.

CAS 号

9061-39-6

结构分类

Saccharides
Polysaccharides

来源

Ascopltyllttm nodosum

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.