Xanthohumol I

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Xanthohumol I

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CAS NO:

688360-06-7

Xanthohumol I 是一种查尔酮，是 Xanthohumol (HY-N1067) 的衍生物。Xanthohumol 是一种胆碱酯酶 (Cholinesterase) 抑制剂，抑制乙酰胆碱酯酶 (AChE) 和丁酰胆碱酯酶 (BChE) 的IC₅₀分别为 71.34 μM 和 32.67 μM。Xanthohumol 的羟基化合物 (3-hydroxy-xanthohumol) 对AChE和BChE也有抑制作用，IC₅₀分别为 51.25 μM 和 63.07 μM。

生物活性

Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is aCholinesterase (ChE)inhibitor, which inhibitsacetylcholinesterase (AChE)andbutyrylcholinesterase (BChE)wihIC₅₀s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect onAChEandBChEwithIC₅₀s of 51.25 μM and 63.07 μM^[1].

IC₅₀& Target^[1]

AChE

BChE

分子量

370.40

Formula

C₂₁H₂₂O₆

CAS 号

688360-06-7

结构分类

Phenols
Polyphenols

来源

Plants
Moraceae
Humulus lupulusL.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.