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2'-O,4'-C-Methyleneguanosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2'-O,4'-C-Methyleneguanosine图片
CAS NO:207131-16-6

LNA-G
2′-O,4′-C-Methyleneguanosine (LNA-G) 是一种反向鸟嘌呤类似物,其中 LNA (locked nucleic acid) 是一种核酸类似物,LNA 修饰可被广泛应用于各种领域,如与互补序列有效的结合亲和力,以及比天然核苷酸更强的核酸酶抗性,在疾病诊断及研究方面的应用提供了巨大的潜力。LNA-G 也可以通过 KOD DNA 聚合酶,可以将 LNA-G 核苷酸整合到 DNA 链中。
生物活性

2′-O,4′-C-Methyleneguanosine (LNA-G) is a reverse guanine analogue, where LNA (locked nucleic acid) is a nucleic acid analogue. LNA modification can be used in a variety of applications such as effective binding affinity to complementary sequences and greater nuclease resistance than natural nucleotides, offering great potential for applications in disease diagnosis and research. LNA-G is also available via KOD DNA polymerase, which allows the integration of LNA-G nucleotides into the DNA strand[1][2].

分子量

295.25

Formula

C11H13N5O5

CAS 号

207131-16-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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