GHRF,mouse

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GHRF,mouse

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

125199-49-7

Mouse growth hormone-releasing factor

GHRF, mouse 是一种小鼠生长激素释放因子，是一种含有 44 个氨基酸的肽。GHRF, mouse 可刺激生长激素的释放和合成。

生物活性

GHRF, mouse, a mouse growth hormone-releasing factor, is a peptide containing 44amino acids. GHRF, mouse stimulates the release and synthesis of growth hormone^[1].

体内研究
(In Vivo)

GHRF, mouse (40 μg/kg, IP, once) significantly increases the GH levels in LI-IGF-I–/– mice^[1].

Animal Model:	LI-IGF-I–/– mice (4 weeks, male and female)^[1]
Dosage:	40 μg/kg
Administration:	IP, once
Result:	The GH levels were significantly higher in LI-IGF-I–/– mice, compared with control mice.

分子量

5032.74

Formula

C₂₂₀H₃₆₅N₆₉O₆₄S

CAS 号

125199-49-7

Sequence Shortening

HVDAIFTTNYRKLLSQLYARKVIQDIMNKQGERIQEQRARLS

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.