SRTCX1002 是一种有效的SIRT1激活剂 (STAC)，通过促进 p65 去乙酰化和抑制 NF-κB 活性来抑制炎症反应。SRTCX1002 抑制刺激诱导的 NF-κB 转录激活和 LPS 诱导的 TNFα 分泌，IC50分别为 0.71 和 7.58 μM。
| 生物活性 | SRTCX1002 is a potent activator ofSIRT1(STAC), suppresses inflammatory responses through promotion of p65 deacetylation and inhibition ofNF-κBActivity. SRTCX1002 suppresses stimuli-inducedNF-κBtranscriptional activation and LPS-induced TNFα secretion with IC50s of 0.71 and 7.58 μM, respectively[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
