ALPK1-IN-1 (Compound A001) 是一种有效的 α-激酶 1 (ALPK1) 抑制剂。ALPK1 是一种胞质内丝/苏氨酸蛋白激酶,通过与叉头相关结构域 (TIFA) 依赖的促炎 NF-κB 信号通路的 TRAF蛋白相互作用,在激活对细菌的先天免疫反应中起重要作用。
生物活性 | ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 (ALPK1). ALPK1 is an intracytoplasmic serine threonine protein kinase that plays an important role in activating the innate immune response to bacteria via TRAF-interacting protein with forkhead-associated domain (TIFA) dependent proinflammatoryNF-κBsignaling[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |