(R)-(+)-Anatabine 是一种 Anatabine 低活性的 S 型异构体。Anatabine 是一种有效的α4β2 nAChR激动剂。Anatabine 通过阻止淀粉样蛋白前体蛋白的 β 裂解，抑制NF-κB激活，并降低淀粉样 β (Aβ) 的产生。Anatabine 具有抗炎作用，可用于神经退行性疾病的研究。
| 生物活性 | (R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potentα4β2nAChRagonist[1]. Anatabine inhibitsNF-κBactivation loweramyloid-β(Aβ)production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment[2][3][4]. |
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| 中文名称 | (R)-(+)-新烟草碱；(R)-(+)-去氢新烟碱 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
