Piribedil dihydrochloride 是一种有效的口服活性多巴胺 D2 和多巴胺 D3 激动剂。
| Cas No. | 1451048-94-4 |
| 别名 | 盐酸吡贝地尔；盐酸双哌嘧啶；盐酸泰舒达 |
| 化学名 | 2-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine |
| Canonical SMILES | C1(CN2CCN(C3=NC=CC=N3)CC2)=CC4=C(OCO4)C=C1 |
| 分子式 | C16H18N4O2.2HCl |
| 分子量 | 371.27 |
| 溶解度 | <8.37mg/ml in Water |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Piribedil is a dopamine D2 receptor (D2R) agonist which also displays antagonist property at hα1A-adrenoceptor (hα1A-AR). References:
[1]. Mark J. Milla, et al. Antiparkinsonian Agent Piribedil Displays Antagonist Properties at Native, Rat, and Cloned, Human α2 -Adrenoceptors: Cellular and Functional Characterization. JPET, 2001, 297 (3) 876-887. |
