CAS NO: | 2763226-84-0 |
生物活性 | Anti-inflammatory agent 17 is a potent and orally active anti-inflammatory agent. Anti-inflammatory agent 17 inhibits the release ofIL-6and TNF-α in vitro experiments without cytotoxicity. Anti-inflammatory agent 17 exhibits anti-inflammatory activity in vivo. Anti-inflammatory agent 17 has the potential for the research of Acute lung injury (ALI)[1]. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Anti-inflammatory agent 17 (compound 5b) (10 μM; 24 h) displays no toxicity in J774a.1 cells[1]. Cell Viability Assay[1]
Immunofluorescence[1]
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体内研究 (In Vivo) | Anti-inflammatory agent 17 (20 mg/kg; intragastric administration) exhibits protective effect on LPS (lipopolysaccharide)-induced ALI in mice[1].
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分子量 | 357.40 | ||||||||||||||||
Formula | C20H23NO5 | ||||||||||||||||
CAS 号 | 2763226-84-0 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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