Clindamycin hydrochloride monohydrate is an oralprotein synthesisinhibitory agent that has the ability to suppress the expression of virulence factors inStaphylococcus aureusat sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of theantibioticbinding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla)^[1].

479.46

C₁₈H₃₆Cl₂N₂O₆S

58207-19-5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.