PDE4-IN-11 is an inhibitor ofphosphodiesteraseisoenzyme 4(PDE4). PDE4-IN-11 displays highly effective bronchodilatory and anti-inflammatory properties, can be used for obstructive or inflammatory airway diseases research^[1][2][3].

PDE4-IN-11 (example 12) exerts function in the monocrotaline reversal model of pulmonary hypertension^[2].
PDE4-IN-11 (compound A1) displays anti-inflammatory, anti-airways hyperreactivity and bronch odilator properties. PDE4-IN-11 also possesses immunosuppressive and TNFα secretion inhibitory activities^[3].

350.39

C₂₁H₁₉FN₂O₂

524734-30-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.