ALK5-IN-8

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ALK5-IN-8

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2705900-81-6

ALK5-IN-8 是一种有效的TGFβRI(ALK5) 抑制剂。ALK5-IN-8 通过阻断 TGFβRI 与配体的结合，抑制 ALK5 在其下游信号蛋白 (Smad2 或 Smad3) 上的磷酸化，从而影响或阻断 TGF-β 信号。ALK5-IN-8 具有研究各种ALK5介导的相关疾病的潜力 (信息摘自专利 WO2021190425A1，化合物1)。

生物活性	ALK5-IN-8 is a potent inhibitor ofTGFβRI(ALK5). ALK5-IN-8 Inhibits the phosphorylation ofALK5on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFβRI to ligands, thereby affecting or blocking TGF-β signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1)^[1].
分子量	350.35
Formula	C₁₉H₁₅FN₄O₂
CAS 号	2705900-81-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.