ALK5-IN-31 (化合物 Ex-08) 是一种选择性的ALK-5抑制剂 (IC50≤10 nM;Ki)，能抑制TGF-β诱导的SMAD信号传导。ALK5-IN-31 有抑制体内肿瘤生长的潜力。ALK5-IN-31 可用于增殖性疾病，如癌症、纤维化疾病、系统性硬化症的研究。
| 生物活性 | ALK5-IN-31 (compound Ex-08) is a selectiveALK-5inhibitor (IC50≤10 nM), inhibitsTGF-β-inducedSMADsignaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such ascancer, fibrotic diseases, and systemic sclerosis[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
