ALK5-IN-32 (化合物 EX-09) 是一种选择性的ALK-5抑制剂 (10 nM<IC50<100 nm)，能抑制TGF-β诱导的SMAD信号传导。ALK5-IN-32 有抑制体内肿瘤生长的潜力。ALK5-IN-32 可用于增殖性疾病，如癌症、纤维化疾病、系统性硬化症的研究。
| 生物活性 | ALK5-IN-32 (compound EX-09) is a selectiveALK-5inhibitor (10 nM<IC50<100 nm), inhibitsTGF-β-inducedSMADsignaling. ALK5-IN-32 has the potential to inhibit growth of tumour in vivo. ALK5-IN-32 can be used in study of proliferative diseases such ascancer, fibrotic diseases, and systemic sclerosis[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
