HM03 trihydrochloride is a potent and selectiveHSPA5(Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity^[1].

HM03 trihydrochloride (0.1-50 μM; 72 hours) exhibits over 50% inhibition at 25 μM concentration in HCT116 cells^[1].
HM03 trihydrochloride forms more binding interactions with HSPA5 and HSPA9 than with the other HSP70 proteins^[1].
HM03 trihydrochloride exhibits promising inhibition activities from cancer cell viability and tumor inhibition assays^[1].

572.35

C₂₆H₃₀Cl₄N₄O₂

1082532-95-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.