DS17701585

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DS17701585

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

DS17701585 (Compound 11) 是一种选择性的、具有口服活性的EP300和CBP抑制剂，对 CBP、EP300、H3K27和SOX2的IC₅₀值分别为 0.040、0.15、0.45 和 0.70 μM。DS17701585 可用于癌症的研究。

生物活性

DS17701585 (Compound 11) is a highly selective, orally activeEP300andCBPinhibitor withIC₅₀values of 0.040, 0.15, 0.45 and 0.70 μM against CBP, EP300,H3K27andSOX2. DS17701585 can be used forcancerresearch^[1].

IC₅₀& Target

H3K27

0.45 μM (IC₅₀)

SOX2

0.70 μM (IC₅₀)

EP300

0.04 μM (IC₅₀)

CBP

0.15 μM (IC₅₀)

分子量

482.55

Formula

C₂₄H₂₆N₄O₅S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.