Repinotan hydrochloride

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

144980-77-8

BAY x 3702

Repinotan hydrochloride (BAY x 3702) 是一种有效的、选择性的、可透过血脑屏障，并具有口服活性的5-HT1A受体激动剂，K_i值为 0.19 nM (小牛海马)， 0.25 nM (大鼠和人类皮层) 和 0.59 nM (大鼠海马)。Repinotan hydrochloride 对其他相关受体的亲和力较弱。Repinotan hydrochloride 具有强效的神经保护作用。

生物活性

Repinotan hydrochloride (BAY x 3702) is a potent, selective, brain-penetrant and orally active5-HT1A receptoragonist, withK_ivalues of 0.19 nM (calf hippocampus), 0.25 nM (rat and human cortex), and 0.59 nM (rat hippocampus Repinotan hydrochloride has a weak affinity for other related receptors. Repinotan hydrochloride has pronounced neuroprotective effects^[1].

Clinical Trial

分子量

436.95

性状

Solid

Formula

C₂₁H₂₅ClN₂O₄S

CAS 号

144980-77-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)