trans-Isoferulic acid

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CAS NO:

25522-33-2

trans-3-Hydroxy-4-methoxycinnamic acid

trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) 是一种从Clematis florida var. plena根中分离出来的芳香酸。trans-Isoferulic acid 具有抗炎活性。trans-isoferulic acid 通过诱导 Nrf2 依赖性血红素加氧酶 1 (HO-1) 抑制NO和PGE2的产生。

生物活性

trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots ofClematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity^[1].trans-isoferulic acid suppressesNOandPGE2production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)^[2].

IC₅₀& Target

Human Endogenous Metabolite

分子量

194.18

Formula

C₁₀H₁₀O₄

CAS 号

25522-33-2

结构分类

Ketones, Aldehydes, Acids

来源

Plants
Ranunculaceae

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.