CAS NO: | 26839-75-8 |
生物活性 | Timolol is aβ-blockeravailable for both topical and systemic administration. Topical Timolol is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension. Timolol can also be used for the research of infantile hemangiomas, hypertension, myocardial infarction, migraine prophylaxis, and atrial fibrillation.Timolol also has cardioprotective effect[1][2]. | ||||||||
IC50& Target |
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体外研究 (In Vitro) | Timolol can significantly prevent the increased lipid peroxidation level of the heart from diabetic rats. Timolol can induce a well-balanced ratio between oxidative stress and antioxidant defense system in the diabetic animals, can have an important cardioprotection against diabetes-induced ERS and associated apoptotic effects[3]. | ||||||||
体内研究 (In Vivo) | Timolol has a cardioprotective effect via inhibition of ERS response in diabetic rats[3].
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Clinical Trial | |||||||||
分子量 | 316.42 | ||||||||
Formula | C13H24N4O3S | ||||||||
CAS 号 | 26839-75-8 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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