CXCR2 antagonist 3

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CXCR2 antagonist 3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2647464-92-2

CXCR2 antagonist 3 (compound 11h) 是 CXC 趋化因子受体 2 (CXCR2) 的有效拮抗剂。CXCR2 antagonist 3 对 CXCR2 表现出两位数的纳摩尔效力，并显着抑制中性粒细胞浸润到气囊中。CXCR2 antagonist 3 可减少中性粒细胞和 MDSC 的浸润，并增强 CD3⁺T 淋巴细胞向 Pan02 肿瘤组织的浸润。

生物活性	CXCR2 antagonist3 (compound 11h) is a potent antagonist ofCXC chemokine receptor2 (CXCR2).CXCR2 antagonist3 demonstrates double-digit nanomolar potencies againstCXCR2and significantly inhibited neutrophil infiltration into the air pouch.CXCR2 antagonist3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3⁺T lymphocytes into the Pan02 tumor tissues^[1].
分子量	362.38
Formula	C₁₇H₁₅FN₂O₄S
CAS 号	2647464-92-2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.