Isolindleyin 是一种丁酰苯，是酪氨酸酶抑制剂，对人酪氨酸酶的Kd值为 54.8 μM。Isolindleyin 具有抗炎和抗黑色素生成活性，可用于缓解疼痛的研究。
| 生物活性 | Isolindleyin, a butyrophenone, is atyrosinaseinhibitor, with aKdof 54.8 μM for humantyrosinase. Isolindleyin exhibits anti-inflammatory, analgesic and anti-melanogenic activities[1]. |
| IC50& Target | Kd: 54.8 μM (human tyrosinase)[1] |
体外研究
(In Vitro) | Isolindley (1-500 μM; 7 days) suppresses melanin synthesis in human epidermal melanocytes[1].
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| 来源 | - Plants
- Polygonaceae
- Rheum officinaleBaill.
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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