KTX-497 是一种IRAK4降解剂，具有口服活性，DC50值为 3 nM。KTX-497 可用于肿瘤学研究。
| 生物活性 | KTX-497 is anIRAK4degrader with aDC50value of 3 nM. KTX-497 can be used for the research of oncology[1]. |
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体外研究
(In Vitro) | KTX-497 has activity for IRAK4 with a DC50value of 3 nM[1].
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体内研究
(In Vivo) | KTX-497 (oral; 10 mg/kg) impacts oral absorption[1].
| Animal Model: | Rat[1] | | Dosage: | 10 mg/kg | | Administration: | Oral | | Result: | Impacted oral absorption. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
