Ranitidine-d6 hydrochloride

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CAS NO:

1185238-09-8

盐酸雷尼替丁 d6 (盐酸盐)

Ranitidine-d6 hydrochloride 是 Ranitidine hydrochloride 的氘代物。Ranitidine hydrochloride 是一种有效的，选择性的，具有口服活性的组胺 H2 受体 (histamine H2-receptor) 拮抗剂，IC₅₀为 3.3 μM，可抑制胃液分泌。Ranitidine hydrochloride 还一种是CYP2C19和CYP2C9的弱抑制剂。

生物活性	Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride. Ranitidine hydrochloride is a potent, selective and orally activehistamine H2-receptorantagonist with anIC₅₀of 3.3 μM that inhibits gastric secretion. Ranitidine hydrochloride is a weak inhibitor ofCYP2C19andCYP2C9^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
分子量	356.90
Formula	C₁₃H₁₇D₆ClN₄O₃S
CAS 号	1185238-09-8
中文名称	盐酸雷尼替丁 d6 (盐酸盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.