CMD178 是一种先导肽，能够持续地通过抑制 IL-2/s IL-2Rα 信号通路来减少 Foxp3 和 STAT5 的表达，并可抑制 Treg细胞的发育。
| 生物活性 | CMD178 is a lead peptide that consistently reduced the expression of Foxp3 andSTAT5induced by IL-2/s IL-2Rα signaling and inhibits Tregcell development[1]. |
体外研究
(In Vitro) | CMD178 (100 mM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells[1].
CMD178 (100 mM) inhibits the development of Tregcells induced by IL2/sIL-2Rα signaling[1].
|
| 分子量 | |
| Formula | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
