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Isoastragaloside I
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isoastragaloside I图片
CAS NO:84676-88-0

异黄芪皂苷I
Isoastragaloside-I
异黄芪皂苷I(Isoastragaloside I)是中药黄芪的一种天然化合物,具有提高脂联素量活性。
生物活性

Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevatingadiponectinproduction. IC50 value: Target: Astragaloside II and isoastragaloside I selectively increasedadiponectinsecretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction ofadiponectinproduction was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of totaladiponectinand selectively increased the composition of its high molecular weight oligomeric complex.

分子量

869.04

性状

Solid

Formula

C45H72O16

CAS 号

84676-88-0

中文名称

异黄芪皂苷 I;异黄芪苷 I

结构分类
  • Terpenoids
  • Triterpenes
来源
  • Plants
  • Leguminosae
  • Astragalus membranaceusvar. mongholicus (Bunge)P.K.Hsiao
  • Plants
  • other families
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO : 50 mg/mL(57.53 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM1.1507 mL5.7535 mL11.5070 mL
5 mM0.2301 mL1.1507 mL2.3014 mL
10 mM0.1151 mL0.5753 mL1.1507 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。

 
 
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