CAS NO: | 9000-69-5 |
生物活性 | Pectin is a heteropolysaccharide, derived from the cell wall of higherplants. Pectin involves in the formation of nanoparticles as a delivery vehicle of drugs. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa[1][2][3]. | |
IC50& Target |
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体外研究 (In Vitro) | Pectin (5 mg/mL; 24, 48, and 72 h) shows low cytotoxicity on HepG2 cells, and can be made into nanoparticles (PPN), encapsulatingPaclitaxel(HY-B0015), decreases the Paclitaxel cytotoxicity (%) from 55.6% to 21.7% at 72 h[1]. | |
体内研究 (In Vivo) | Pectin serves as the nanoparticles encapsulatingPaclitaxel(HY-B0015), (20 mg/kg; i.v.; single dose) significantly delays plasma clearance with detection of Paclitaxel possible up to 48 h in Balb/c mice[1]. | |
Clinical Trial | ||
CAS 号 | 9000-69-5 | |
结构分类 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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