PfGSK3/PfPK6-IN-2

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PfGSK3/PfPK6-IN-2

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CAS NO:

2797225-47-7

PfGSK3/PfPK6-IN-2 是一种有效的PfGSK3/PfPK6(Plasmodium falciparumGSK3/PK6) 双重抑制剂 (IC₅₀分别为 172 nM 和 11 nM)。PfGSK3/PfPK6-IN-2 可用于疟疾的研究。

生物活性	PfGSK3/PfPK6-IN-2 is a potent dualPfGSK3/PfPK6(PlasmodiumfalciparumGSK3/PK6) inhibitor (IC₅₀: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria^[1].
IC₅₀& Target	Plasmodium falciparumGSK3/PK6 (PfGSK3/PfPK6)^[1]
体外研究 (In Vitro)	PfGSK3/PfPK6-IN-2 (compound 23d) inhibitsP. falciparum3D7 load in erythrocytes (EC₅₀: 552 nM)^[1]. PfGSK3/PfPK6-IN-2 (2 μM) shows cytotoxicity against HepG2 cells^[1].
分子量	502.46
Formula	C₂₄H₂₅Cl₂N₅OS
CAS 号	2797225-47-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.