AZ7550-d5 是 AZ7550 (HY-B0794) 的氘代物。AZ7550 是 Osimtinib (AZD9291; HY-15772) 的一种活性代谢物，AZ7550 抑制 IGF1R 活性，IC50 为 1.6 μM。
| 生物活性 | AZ7550-d5 is the deuterium labeled AZ7550 (HY-B0794). AZ7550, an active metabolite of Osimtinib (AZD9291; HY-15772), inhibits the activity of IGF1R with an IC50 of 1.6 μM[1][2]. |
体外研究
(In Vitro) | AZ7550-d5 (compound M6) has the relative abundance of metabolites generated in human liver microsomes of 15.58%[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
