CAS NO: | 195611-82-6 |
生物活性 | GW7604 is an antiestrogen. GW7604 is the metabolite of GW5638, which is a high affinityestrogen receptor(ER) antagonist[1]. | |||||||||
体外研究 (In Vitro) | GW7604 is the presumed metabolite of GW5638 in breast (MCF-7) and endometrial (ECC-1) cell lines. GW7604 (0.1 nM-1 μM; 24 hours) inhibits both Estradiol (1 nM) and 4-hydroxytamoxifen (4-OHT; 10 and 100 nM) induction of TGF-alpha in a concentration related manner (1-1000 nM) in MDA-MB-231 cells[1]. Western Blot Analysis[1]
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分子量 | 370.44 | |||||||||
性状 | Solid | |||||||||
Formula | C25H22O3 | |||||||||
CAS 号 | 195611-82-6 | |||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
储存方式 |
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