2-脱氧尿苷可增加染色体断裂并导致胸苷酸合成酶活性降低。
| Cas No. | 951-78-0 |
| 别名 | 2'-脱氧尿苷; 2-脱氧尿苷 |
| 化学名 | 4-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one |
| Canonical SMILES | OC[C@](O1)([H])[C@](O)([H])C[C@]1([H])N2C=CC(O)=NC2=O |
| 分子式 | C9H12N2O5 |
| 分子量 | 228.2 |
| 溶解度 | ≥ 22.8mg/mL in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine. References:
[1]. Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5. |
