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(R)-Verapamil D7 HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装:50mg, 100mg, 250mg
规格:≥98%

(R)-Verapamil D7 HCl ((R)-(+)-Verapamil D7 HCl) is a deuterated form of (R)-Verapamil HCl. (R)-Verapamil HCl ((R)-(+)-Verapamil HCl) is a P-Glycoprotein inhibitor. (R)-Verapamil HCl blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer drugs. References: [1]. Plumb JA, et al. The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific. Biochem Pharmacol. 1990 Feb 15;39(4):787-92. [2]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22.

纯度:≥98%

 
 
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