(±)-Pantothenic acid

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CAS NO:

599-54-2

(±)-Pantothenate
(±)-Vitamin B5

(±)-Pantothenic acid ((±)-Pantothenate) 是一种 B 族维生素，是哺乳动物细胞中辅酶 A (CoA) 生物合成所需的必需维生素。Pantothenic acid 对丙戊酸 (VPA) 诱导的 CD-1 小鼠神经管缺陷 (NTD) 有保护作用。

生物活性	(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice^[1].
体内研究 (In Vivo)	(±)-Pantothenic acid (3 × 200 mg/kg; IP, single dosage) blocks VPA-induced decreases in c-Myb and Pim-1 protein expression; reduces the incidence of NTD to 6.8% in VPA-injected CD-1 mice, while incidence of the untreated group is 23.6%^[1].
分子量	219.23
Formula	C₉H₁₇NO₅
CAS 号	599-54-2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.