[DAla4] Substance P(4-11)

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CAS NO:

81381-50-2

[DAla4] Substance P (4-11) 是 Substance P (Substance P (HY-P0201)) 的类似物，可抑制¹²⁵I-Bolton Hunter 偶联的 Eledoisin (IC₅₀为 0.5 μM) 和¹²⁵I-Bolton Hunter 偶联的 Substance P (IC₅₀为 0.15 μM) 与大鼠大脑皮层膜的结合。

生物活性	[DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of¹²⁵I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC₅₀of 0.5 μM) and¹²⁵I-Bolton Hunter-conjugated Substance P (IC₅₀of 0.15 μM) to rat brain cortex membranes^[1].
体外研究 (In Vitro)	Eledoisin 和 Substance P 是速激肽的一类肽成员，它们具有相似的生物活性谱。[DAla4] Substance P (4-11) ([D-Ala⁰-(5-11)]SP) 抑制¹²⁵I-Bolton Hunter-conjugated 偶联的 Eledoisin 和¹²⁵I-Bolton Hunter 偶联的 Substance P 与大鼠大脑皮层膜的结合^[1]。
分子量	940.12
Formula	C₄₄H₆₅N₁₁O₁₀S
CAS 号	81381-50-2
Sequence Shortening	{D-Ala}-QQFFGLM-NH2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.