(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 是Neurokinin B(Neurokinin Receptor) 的竞争性拮抗剂，pA2 为 5.5，对 Substance P 或 Neurokinin A 没有影响。
| 生物活性 | (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist ofNeurokinin B(Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1]. |
体内研究
(In Vivo) | 在大鼠中，(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) 显着减少 Substance P- 和 Neurokinin B-， 但不减少乙酰胆碱或 Neurokinin A 诱导的流涎。(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 可将麻醉大鼠的血压降低 35% 至 40%[2]。
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| 分子量 | |
| Formula | |
| CAS 号 | |
| Sequence Shortening | D-{D-Pro}-HDF-{D-Trp}-V-{D-Trp}-L-{Nle}-NH2 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
