Brexpiprazole S-oxide (DM-3411) is the S-oxidized, CYP3A4-mediated and major metabolite of Brexpiprazole (Rexulti; OPC34712; OPC-34712), which is an approved atypical antipsychotic medication and a partial agonist of human 5-HT1A as well as dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM.
纯度:≥98%
CAS:1191900-51-2