Chloroquine-d4 phosphate

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磷酸氯喹 d4 (磷酸盐)

Chloroquine-d4 phosphate 是 Chloroquine phosphate 的氘代物。Chloroquine phosphate 是一种广泛用于疟疾和类风湿性关节炎的抗疟疾和抗炎剂。Chloroquine phosphate 是autophagy和toll-like receptors (TLRs)的抑制剂。Chloroquine phosphate 有效抑制SARS-CoV-2(COVID-19) 感染 (E

生物活性	Chloroquine-d4 phosphate is the deuterium labeled Chloroquine phosphate. Chloroquine phosphate is anantimalarialand anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is anautophagyandtoll-like receptors (TLRs)inhibitor. Chloroquine phosphate is highly effective in the control ofSARS-CoV-2 (COVID-19)infectionin vitro (EC₅₀=1.13 μM)^[1]^[2]^[3]^[4].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
分子量	519.89
Formula	C₁₈H₂₈D₄ClN₃O₈P₂
中文名称	磷酸氯喹 d4 (磷酸盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.