Amphotericin X1

立即咨询

Amphotericin X1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

136135-57-4

两性霉素 X1

Amphotericin X1 是一种 Amphotericin B 的 13-O-甲基衍生物，具有良好的抗真菌活性。Amphotericin X1 抑制白色念珠菌 33/079，副念珠菌 937A，新型隐球菌 451，黑曲霉 57A 和烟曲霉的 MIC 值分别为1 μg/mL，8 μg/mL，1 μg/mL，2 μg/mL 和 2 μg/mL。

生物活性	Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibitsCandida albicans33/079,C.parapsilosis937A,Cryptococcus neoformans451,Aspergillus niger57AandA.fumigatuswith MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively^[1].
IC₅₀& Target	MIC: 1 μg/mL (Candida albicans33/079), 8 μg/mL (C.parapsilosis937A), 1 μg/mL (Cryptococcus neoformans451), 2 μg/mL (Aspergillus niger57A) and 2 μg/mL (A.fumigatus)^[1]
体外研究 (In Vitro)	Amphotericin X1 (compound 4) shows interesting antifungal activity combined with a pronounced reduction in haemolytic activity (EH₅₀of 42 μg/mL) against mammalianerythrocytes in vitro^[1].
分子量	938.11
Formula	C₄₈H₇₅NO₁₇
CAS 号	136135-57-4
中文名称	两性霉素 X1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.