ATX inhibitor 11 (compound 13c) 是一种有效的ATX(autotaxin) 抑制剂，其IC50为 2.7 nM。在小鼠纤维化模型中，ATX inhibitor 11 可缓解纤维化组织的严重程度，有效减少纤维化生物标志物 α-SMA 的沉积。ATX inhibitor 11 可用于肺纤维化研究。
| 生物活性 | ATX inhibitor 11 (compound 13c) is a potentATX(autotaxin) inhibitor, with anIC50of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research[1]. |
| IC50& Target | Autotaxin 2.7 ± 1 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
