ATX inhibitor 15 (compound 30) 是一种基于吲哚的氨基甲酸酯衍生物，一种有效的自粘蛋白 (ATX) 抑制剂，IC50为 2.17 nM。ATX inhibitor 15 抑制体内 ATX 和促纤维化因子的基因表达。ATX inhibitor 15 在博来霉素攻击的小鼠肺纤维化模型中具有肺保护作用。
| 生物活性 | ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potentautotaxin(ATX)inhibitor with anIC50of 2.17 nM. ATX inhibitor 15 inhibits in vivo ATX and the gene expression of pro-fibrotic factors. ATX inhibitor 15 has lung protection effects in Bleomycin challenged mice lung fibrosis model[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
