Bonducellpin D

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Bonducellpin D

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

197781-85-4

Bonducellpin D 是一种从Caesalpinia minax中分离出来呋喃二萜类内酯。 Bonducellpin D 表现出对SARS-CoV M^pro和MERS-CoV M^pro的广谱抑制能力，K_i值分别为 467.11 和 284.86 nM。Bonducellpin D 在体外表现出中等的抗癌活性。

生物活性

Bonducellpin D is a furanoditerpenoid lactone isolated fromCaesalpinia minax. Bonducellpin D exhibits broad-spectrum inhibition potential againstSARS-CoVM^proandMERS-CoV M^pro, with anK_iof 467.11 and 284.86 nM, respectively. Bonducellpin D also exhibits moderate anti-cancer activity in vitro^[1]^[2]^[3].

IC₅₀& Target

Ki: 467.11 nM (SARS-CoV Mpro), 284.86 nM (MERS-CoV Mpro)^[1]

分子量

404.45

性状

Solid

Formula

C₂₂H₂₈O₇

CAS 号

197781-85-4

结构分类

Terpenoids
Other Terpenoids

来源

Plants
Leguminosae
Caesalpinia minaxHance

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month