Medrysone 是一种皮质类固醇，在眼科中用于治疗眼部炎症。
| Cas No. | 2668-66-8 |
| 别名 | 甲羟松; HMS; 6α-Methyl-11β-hydroxyprogesterone |
| 化学名 | (6α,11β)-11-hydroxy-6-methyl-pregn-4-ene-3,20-dione |
| Canonical SMILES | C[C@@]12[C@](CC[C@@H]2C(C)=O)([H])[C@]3([H])C[C@H](C)C4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C1)=O |
| 分子式 | C22H32O3 |
| 分子量 | 344.5 |
| 溶解度 | ≤1mg/ml in ethanol;1mg/ml in methanol;1mg/ml in acetonitrile |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 6α-Methyl-11β-hydroxyprogesterone is a synthetic glucocorticoid which has been used in the treatment of inflammatory eye diseases. 6α-Methyl-11β-hydroxyprogesterone is a corticosteroid with anti-inflammatory properties which has been discontinued in the United States. The structure of 6α-Methyl-11β-hydroxyprogesterone is very similar to progesterone. Neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone [1, 2]. References:
[1] The dictionary of drugs: chemical data: chemical data, structures and bibliographies[M]. Springer, 2014.
[2] SPAETH G L. Hydroxymethylprogesterone: An anti-inflammatory steroid without apparent effect on intraocular pressure[J]. Archives of Ophthalmology, 1966, 75(6): 783-787. |
