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Khellin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Khellin图片
CAS NO:82-02-0

呋喃并色酮
Khellin 是一种呋喃并色酮,能从Ammi visnugaL. 中提取得到。Khellin 是一种EGFR抑制剂,其IC50为 0.15 μM。Khelline 在体外具有抗增殖活性。Khellin 具有抗痉挛和冠状动脉舒张作用。
生物活性

Khellin is a furochromone that can be isolated fromAmmi visnugaL.. Khellin is anEGFRinhibitor with anIC50of 0.15 μM. Khelline has anti-proliferative activity in vitro. Khellin has antispasmodic and coronary vasodilator effects[1][2].

IC50& Target

IC50: 0.15 μM (EGFR)[1]

体外研究
(In Vitro)

Khelline exhibits anti-proliferative activity for MCF-7 cells and Hela cells[1].
Khellin inhibits the pathways of Ca2+influx which are activated by both noradrenaline and high K+[2].

分子量

260.24

Formula

C14H12O5

CAS 号

82-02-0

中文名称

呋喃并色酮

结构分类
  • Phenylpropanoids
  • Lignans
来源
  • Plants
  • Umbelliferae
  • Ammi visnaga(L.) Lam
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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