SDZ NKT 343 是一种选择性的、口服活性的 NK1 受体拮抗剂,对人 NK1 受体的 IC50 为 0.62 nM。
Cas No. | 180046-99-5 |
化学名 | (S)-N2-((S)-1-(benzyl(methyl)amino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-N1-(2-nitrophenyl)pyrrolidine-1,2-dicarboxamide |
Canonical SMILES | O=C([C@H]1N(C(NC2=CC=CC=C2[N+]([O-])=O)=O)CCC1)N[C@H](C(N(C)CC3=CC=CC=C3)=O)CC4=CC=C5C(C=CC=C5)=C4 |
分子式 | C33H33N5O5 |
分子量 | 579.65 |
溶解度 | <57.97mg/ml in ethanol;<57.97mg/ml in DMSO |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |