Quetiapine sulfoxide hydrochloride (Quetiapine S-oxide hydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic^[1]. Quetiapine is a 5-HT receptors agonist and adopamine receptor antagonist^[2].

The C_maxvalue (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUC_lastvalue is estimated for Quetiapine sulfoxide (1,286±458 ngoh/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing^[1].

435.97

Solid

C₂₁H₂₆ClN₃O₃S

喹硫平亚砜盐酸盐

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)