L-Phenylalanine-13C9,15N,d8

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CAS NO:

1994331-22-4

(S)-2-Amino-3-phenylpropionic acid-13C9,15N,d8

L-Phenylalanine-13C9,15N,d8 ((S)-2-Amino-3-phenylpropionic acid-13C9,15N,d8) 是带有 13C，15N 标记和氘代标记的 L-Phenylalanine。L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) 是分离自大肠杆菌的必需氨基酸。L-Phenylalanine 是一种电压依赖性 α2δ 亚基Ca2⁺通道拮抗剂，K_i为 980 nM。L-Phenylalanine 是NMDARs(K_B573 μM) 和非NMDARs的甘氨酸和谷氨酸结合位点的竞争性拮抗剂。L-Phenylalanine 广泛用于食品香料和药品的生产中。

生物活性

L-Phenylalanine-13C9,15N,d8 ((S)-2-Amino-3-phenylpropionic acid-13C9,15N,d8) is the deuterium, 13C-, and 15-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated fromEscherichia coli. L-Phenylalanine is aα2δ subunit of voltage-dependent Ca⁺channelsantagonist with aK_iof 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites ofN-methyl-D-aspartate receptors (NMDARs)(K_Bof 573 μM ) andnon-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals^[1]^[2]^[3]^[4].

IC₅₀& Target

NMDA Receptor

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

分子量

183.17

Formula

¹³C₉H₃D₈¹⁵NO₂

CAS 号

1994331-22-4

中文名称

L-苯丙氨酸 13C9,15N,d8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.